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Recombinant Human Enterokinase



Catalog Number : 450-48C

Description

Proteases (also called Proteolytic Enzymes, Peptidases, or Proteinases) are enzymes that hydrolyze the amide bonds within proteins or peptides. Most proteases act in a specific manner, hydrolyzing bonds at or adjacent to specific residues or a specific sequence of residues contained within the substrate protein or peptide. Proteases play an important role in most diseases and biological processes including prenatal and postnatal development, reproduction, signal transduction, the immune response, various autoimmune and degenerative diseases, and cancer. They are also an important research tool, frequently used in the analysis and production of proteins. Enterokinase sequentially cleaves carboxyl side of D-D-D-D-K. Human Enterokinase is expressed as a linear 1019 amino acid polypeptide precursor glycoprotein. Proteolytic processing of this precursor generates the biologically active form of Enterokinase, which consists of two polypeptide chains (heavy chain and light chain) held together by a single disulfide bond, resulting in formation of a biologically active heterodimer. The heavy chain consists of 784 amino acid residues, and the light consists of 235 amino acid residues.

Additional Information

Source:
CHO cells
 
Purity:
Above 90% as determined by SDS-PAGE Analysis.
 
Cross Reactivity:
NULL
 
Biological Activity
Sequentially cleaves carboxyl side of D-D-D-D-K.
 
AA Sequence

Hea vychain:< /b>LTIKES QRGAALGQS HEARATFKI TSGVTYNPN LQDKLSVDF KVLAFDLQQ MIDEIFLSS NLKNEYKNS RVLQFENGS IIVVFDLFF AQWVSDQNV KEELIQGLE ANKSSQLVT FHIDLNSVD ILDKLTTTS HLATPGNVS IECLPGSSP CTDALTCIK ADLFCDGEV NCPDGSDED NKMCATVCD GRFLLTGSS GSFQATHYP KPSETSVVC QWIIRVNQG LSIKLSFDD FNTYYTDIL DIYEGVGSS KILRASIWE TNPGTIRIF SNQVTATFL IESDESDYV GFNATYTAF NSSELNNYE KINCNFEDG FCFWVQDLN DDNEWERIQ GSTFSPFTG PNFDHTFGN ASGFYISTP TGPGGRQER VGLLSLPLD PTLEPACLS FWYHMYGEN VHKLSINIS NDQNMEKTV FQKEGNYGD NWNYGQVTL NETVKFKVA FNAFKNKIL SDIALDDIS LTYGICNGS LYPEPTLVP TPPPELPTD CGGPFELWE PNTTFSSTN FPNSYPNLA FCVWILNAQ KGKNIQLHF QEFDLENIN DVVEIRDGE EADSLLLAV YTGPGPVKD VFSTTNRMT VLLITNDVL ARGGFKANF TTGYHLGIP EPCKADHFQ CKNGECVPL VNLCDGHLH CEDGSDEAD CVRFFNGTT NNNGLVRFR IQSIWHTAC AENWTTQIS NDVCQLLGL GSGNSSKPI FSTDGGPFV KLNTAPDGH LILTPSQQC LQDSLIRLQ CNHKSCGKK LAAQDITPK

Lig htChain:< /b>IVGGSN AKEGAWPWV VGLYYGGRL LCGASLVSS DWLVSAAHC VYGRNLEPS KWTAILGLH MKSNLTSPQ TVPRLIDEI VINPHYNRR RKDNDIAMM HLEFKVNYT DYIQPICLP EENQVFPPG RNCSIAGWG TVVYQGTTA NILQEADVP LLSNERCQQ QMPEYNITE NMICAGYEE GGIDSCQGD SGGPLMCQE NNRWFLAGV TSFGYKCAL PNRPGVYAR VSRFTEWIQ SFLH

Protein Cross Reactivity: NULL

Availability: In stock

Size Price Qty
10µg
$80.00
50µg
$195.00
100µg
$300.00
500µg
$900.00
1mg
$1,500.00