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Recombinant Human CNTF



Catalog Number : 450-13

Description

CNTF is a potent neural factor that was originally characterized as a vital factor for the survival of chick ciliary neurons in vitro. CNTF is also important for the survival of other neural cell types including primary sensory neurons, motor neurons, basal forebrain neurons and type 2 astrocytes. CNTF is highly conserved across species and exhibits cross-species bioactivity. Recombinant human CNTF is synthesized as a 199 amino acid polypeptide (22.8 kDa) lacking a hydrophobic N-terminal signal for secretion.

Additional Information

Source:
E. Coli
 
Purity:
Above 98% as determined by SDS-PAGE Analysis.
 
Cross Reactivity:
Hamster, Mouse, Rat
 
Biological Activity
Determined by its ability to stimulate proliferation of human TF-1 cells using an ED50 concentration range of 50-150 ng/ml.
 
AA Sequence
AFTEHSPLT PHRRDLCSR SIWLARKIR SDLTALTQS YVKHQGLNK NINLDSADG MPVASTDQW SQLTQAQRL QQNLQAYRT FHVLLARLL QDQQVHFTP TQGDFHQAI HTLLLQVAA FAYQIQQLM ILLQYKIPR NQADGMPIN VGDGGLFQK KLWGLKVLQ QLSQWTVRS IHDLRFISS HQTGIPARG SHYIANNKK M
Research Interest: Stem Cell Research, Apoptosis, Angiogenesis, Neurosciences, Bone Biology, Inflammation, Metabolic Regulation and Diabetes
Cell Type: Stem Cells, Neurons
Protein Cross Reactivity: Hamster, Mouse, Rat

Availability: In stock

Size Price Qty
5µg
$80.00
20µg
$195.00
100µg
$600.00
500µg
$1,800.00
1mg
$3,000.00