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Recombinant Human Chemerin



Catalog Number : 300-66

Description

Chemerin is a secreted chemoattractant protein that can signal through the chemokine like receptor-1 (CMKLR1). It is expressed in various tissues, including white adipose tissue, and circulates in blood as an inactive 143 amino acid precursor protein. Biologically active Chemerin is generated by proteolytic removal of C-terminal residues by several circulating proteases. Chemerin acts as a chemoattractant for cells expressing the CMKLR1 receptor, which includes certain dendritic cells, macrophages, and adipocytes. Recombinant human Chemerin is a 15.6 kDa protein consisting of 135 amino acid residues.

Additional Information

Source:
E. Coli
 
Purity:
Above 98% as determined by SDS-PAGE Analysis.
 
Cross Reactivity:
NULL
 
Biological Activity
Determined by its ability to chemoattract human immature dendritic cells using a concentration range of 1.0-100.0 ng/ml.
 
AA Sequence
ELTEAQRRG LQVALEEFH KHPPVQWAF QETSVESAV DTPFPAGIF VRLEFKLQQ TSCRKRDWK KPECKVRPN GRKRKCLAC IKLGSEDKV LGRLVHCPI ETQVLREAE EHQETQCLR VQRAGEDPH SFYFPGQFA
Research Interest: Immunology, Metabolic Regulation and Diabetes
Cell Type: Monocytes and Macrophages, Dendritic Cells
Protein Cross Reactivity: NULL

Availability: In stock

Size Price Qty
5µg
$80.00
25µg
$195.00
100µg
$600.00
500µg
$1,800.00
1mg
$3,000.00