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Recombinant Human BMP-4



Catalog Number : 120-05

Description

Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-β superfamily of structurally related signaling proteins. Members of this superfamily are widely distributed throughout the body and are involved in diverse physiological processes during both pre- and postnatal life. Like BMP-7, BMP-4 is involved in the development and maintenance of bone and cartilage. Reduced expression of BMP-4 is associated with a number of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Recombinant human BMP-4, expressed in HeLa cells, is a 31-36 kDa homodimeric glycoprotein.

Additional Information

Source:
HeLa cells
 
Purity:
Above 97% as determined by SDS-PAGE Analysis.
 
Cross Reactivity:
NULL
 
Biological Activity
Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells.
 
AA Sequence
HHSQRARKK NKNCRRHSL YVDFSDVGW NDWIVAPPG YQAFYCHGD CPFPLADHL NSTNHAIVQ TLVNSVNSS IPKACCVPT ELSAISMLY LDEYDKVVL KNYQEMVVE GCGCR
Research Interest: Stem Cell Research, Apoptosis, Angiogenesis, Bone Biology, Proliferation and Cell Cycle
Protein Cross Reactivity: NULL

Availability: In stock

Size Price Qty
1µg
$80.00
5µg
$195.00
100µg
$1,200.00
500µg
$4,200.00
1mg
$7,000.00