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Recombinant Human AITRL



Catalog Number : 310-22

Description

AITRL, a member of the TNF superfamily, is expressed in endothelial cells, and signals through the AITR receptor. AITRL regulates T-cell proliferation and survival, and effectuates the interaction between T lymphocytes and endothelial cells. The AITRL gene codes for a type II transmembrane protein comprised of 177 amino acids, including a 28 amino acid cytoplasmic region, a 21 amino acid transmembrane domain and a 128 amino acid extracellular domain. Recombinant human soluble AITRL is a 14.4 kDa protein, containing 127 amino acid residues corresponding to the extracellular domain of AITRL.

Additional Information

Source:
E. Coli
 
Purity:
Above 98% as determined by SDS-PAGE Analysis.
 
Cross Reactivity:
NULL
 
Biological Activity
Determined by its ability to stimulate IL-8 production by human PBMC using a concentration range of 1.0-10.0 ng/ml.
Please Note: Results may vary with PBMC donors.
 
AA Sequence
METAKEPCM AKFGPLPSK WQMASSEPP CVNKVSDWK LEILQNGLY LIYGQVAPN ANYNDVAPF EVRLYKNKD MIQTLTNKS KIQNVGGTY ELHVGDTID LIFNSEHQV LKNNTYWGI ILLANPQFI
Research Interest: Stem Cell Research, Apoptosis, Immunology
Cell Type: T Cells, Endothelial Cells
Protein Cross Reactivity: NULL

Availability: In stock

Size Price Qty
5µg
$80.00
20µg
$195.00
100µg
$850.00
500µg
$3,120.00
1mg
$5,200.00