Recombinant Human AITRL
Catalog Number : 310-22
description
AITRL, a member of the TNF superfamily, is expressed in endothelial cells, and signals through the AITR receptor. AITRL regulates T-cell proliferation and survival, and effectuates the interaction between T lymphocytes and endothelial cells. The AITRL gene codes for a type II transmembrane protein comprised of 177 amino acids, including a 28 amino acid cytoplasmic region, a 21 amino acid transmembrane domain and a 128 amino acid extracellular domain. Recombinant human soluble AITRL is a 14.4 kDa protein, containing 127 amino acid residues corresponding to the extracellular domain of AITRL.
Additional Information
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Source:
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E. Coli
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Purity:
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Above 98% as determined by SDS-PAGE Analysis.
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Cross Reactivity:
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NULL
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Biological Activity
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Determined by its ability to stimulate IL-8 production by human PBMC using a concentration range of 1.0-10.0 ng/ml.
Please Note: Results may vary with PBMC donors. |
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AA Sequence
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METAKEPCM AKFGPLPSK WQMASSEPP CVNKVSDWK LEILQNGLY LIYGQVAPN ANYNDVAPF EVRLYKNKD MIQTLTNKS KIQNVGGTY ELHVGDTID LIFNSEHQV LKNNTYWGI ILLANPQFI
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| Research Interest: | Stem Cell Research, Apoptosis, Immunology |
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| Cell Type: | T Cells, Endothelial Cells |
| Application: | FA |
| Protein Cross Reactivity: | NULL |