Prostaglandin E2
Catalog Number : 3632464
description
Prostaglandin E2 is the most biologically active prostaglandin and exists in some level in nearly all cell types. It binds to EP1, EP2, Ep3, and Ep4 receptors and is involved in smooth muscle relaxation, inflammation, fertility, sleep cycle regulation, and gastric mucosal integrity.
Additional Information
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Applications:
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FA
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Synonyms:
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Dinoprostone, PGE2, 13E-dien-1-oic acid
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Formulation:
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Crystalline solid
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Chemical Name:
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(Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]hept-5-enoic acid
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Molecular Formula:
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C20H32O5 |
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Molecular Weight: |
352.5
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CAS Number
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363-24-6
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Purity:
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≥98%
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Storage Conditions:
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Product should be kept at-20°C.
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References:
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Sheng, H., Shao, J., Morrow, J. D., Beauchamp, R. D., & DuBois, R. N. (1998). Modulation of apoptosis and Bcl-2 expression by prostaglandin E2 in human colon cancer cells. Cancer Research, 58(2), 362-366. Betz, M., & Fox, B. S. (1991). Prostaglandin E2 inhibits production of Th1 lymphokines but not of Th2 lymphokines. The Journal of Immunology, 146(1), 108-113. Kunkel, S. L., Spengler, M., May, M. A., Spengler, R., Larrick, J., & Remick, D. (1988). Prostaglandin E2 regulates macrophage-derived tumor necrosis factor gene expression. Journal of Biological Chemistry, 263(11), 5380-5384. |