NBQX disodium salt
Catalog Number : 4798694
description
NBQX is a potent and selective AMPA and kainate receptor antagonist that is used to counter glutamate excitotoxicity. It is reported to exhibit anticonvulsant activity in rodent models. NBQX disodium salt is the more water soluble version of this reagent.
Additional Information
Applications:
|
FA
|
Synonyms:
|
1,2,3,4-Tetrahydro-6-nitro-2,3-dioxo-benzo[f]quinoxaline-7-sulfonamide disodium salt, FG9202 disodium
|
Formulation:
|
Crystalline solid
|
Chemical Name:
|
disodium;6-nitro-7-sulfamoylbenzo[f]quinoxaline-2,3-diolate
|
Molecular Formula:
|
C12H6N4O6S 2Na |
Molecular Weight: |
380.2
|
CAS Number
|
479347-86-9
|
Purity:
|
≥98%
|
Storage Conditions:
|
Product should be kept at -20°C.
|
References:
|
Chapman, A. G., Smith, S. E., & Meldrum, B. S. (1991). The anticonvulsant effect of the non-NMDA antagonists, NBQX and GYKI 52466, in mice.Epilepsy research, 9(2), 92-96. Gill, R., Nordholm, L., & Lodge, D. (1992). The neuroprotective actions of 2, 3-dihydroxy-6-nitro-7-sulfamoyl-benzo (F) quinoxaline (NBQX) in a rat focal ischaemia model. Brain research, 580(1), 35-43. Wrathall, J. R., Choiniere, D., & Teng, Y. D. (1994). Dose-dependent reduction of tissue loss and functional impairment after spinal cord trauma with the AMPA/kainate antagonist NBQX. The Journal of neuroscience,14(11), 6598-6607. |