Losartan potassium
Catalog Number : 1249980
description
Losartan potassium is a selective angiotensin II receptor type 1 (AT1) antagonist with antihypertensive properties. It is metabolized to produce the 5-carboxylic acid metabolite (EXP3174) and is reported to lower blood pressure. It is currently being researched as a potential treatment for COVID-19 for its potential to mitigate or possibly attenuate the symptoms of COVID-19.
Additional Information
Applications: | FA |
Synonyms: | Cozaar, MK 954, MK-954, DuP-753 |
Formulation: | Crystalline solid |
Chemical Name: | [2-butyl-5-chloro-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol |
Molecular Formula: | C22H22ClN6O K |
Molecular Weight: | 461.0 |
CAS Number | 124750-99-8 |
Purity: | 98% |
Storage Conditions: | Product should be kept at -20°C. |
References: | Goa, K. L., & Wagstaff, A. J. (1996). Losartan potassium. Drugs, 51(5), 820-845. Sica, D. A., Gehr, T. W., & Ghosh, S. (2005). Clinical pharmacokinetics of losartan. Clinical pharmacokinetics, 44(8), 797-814. Zeinalian, M., Salari-Jazi, A., Jannesari, A., & Khanahmad, H. (2020). A potential protective role of losartan against coronavirus-induced lung damage. Infection Control & Hospital Epidemiology, 1-2. |