Kartogenin
Catalog Number : 4723153
description
Kartogenin binds to filamin A, an actin-binding protein, and inhibits its interaction with core-binding factor Beta. This interaction is reported to induce cartilage differentiation and potently induce human mesenchymal stem cells into chondrocytes.
Additional Information
Applications: | FA |
Synonyms: | 2-([1,1'-Biphenyl]-4-ylcarbamoyl)benzoic acid, N-Biphenyl-4-yl-phthalamic acid, ST50171256 |
Formulation: | Crystalline solid |
Chemical Name: | 2-[(4-phenylphenyl)carbamoyl]benzoic acid |
Molecular Formula: | C20H15NO3 |
Molecular Weight: | 317.3 |
CAS Number | 4727-31-5 |
Purity: | ≥98% |
Storage Conditions: | Product should be kept at -20°C. |
References: | Marini, J. C., & Forlino, A. (2012). Replenishing cartilage from endogenous stem cells. New England Journal of Medicine, 366(26), 2522-2524. Hayek, A., Kerstetter-Fogle, A. E., Sachlos, E., & Bollenbach, T. (2012). Kartogenin: a game-changer in regenerative medicine. Regenerative medicine, (7), 475. Ray, K. (2012). Therapy: Tissue engineering: harnessing stem cells in cartilage repair. Nature Reviews Rheumatology, 8(6), 308-308. |