Kartogenin
Catalog Number : 4723153
description
Kartogenin binds to filamin A, an actin-binding protein, and inhibits its interaction with core-binding factor Beta. This interaction is reported to induce cartilage differentiation and potently induce human mesenchymal stem cells into chondrocytes.
Additional Information
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Applications:
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FA
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Synonyms:
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2-([1,1'-Biphenyl]-4-ylcarbamoyl)benzoic acid, N-Biphenyl-4-yl-phthalamic acid, ST50171256
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Formulation:
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Crystalline solid
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Chemical Name:
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2-[(4-phenylphenyl)carbamoyl]benzoic acid
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Molecular Formula:
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C20H15NO3 |
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Molecular Weight: |
317.3
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CAS Number
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4727-31-5
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Purity:
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≥98%
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Storage Conditions:
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Product should be kept at -20°C.
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References:
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Marini, J. C., & Forlino, A. (2012). Replenishing cartilage from endogenous stem cells. New England Journal of Medicine, 366(26), 2522-2524. Hayek, A., Kerstetter-Fogle, A. E., Sachlos, E., & Bollenbach, T. (2012). Kartogenin: a game-changer in regenerative medicine. Regenerative medicine, (7), 475. Ray, K. (2012). Therapy: Tissue engineering: harnessing stem cells in cartilage repair. Nature Reviews Rheumatology, 8(6), 308-308. |