Kainic Acid Monohydrate
Catalog Number : 5806232
description
Kainic acid is a potent neuroexcitatory amino acid that acts as a neurotoxin in high doses. It was originally isolated from seaweed and is used in the study of the physiological effect of excitotoxicity and assess the neuroprotective capabilities of potential therapeutics.
Additional Information
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Applications:
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FA
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Synonyms:
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Digenin, Kainic acid hydrate
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Formulation:
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Crystalline solid
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Chemical Name:
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(2S,3S,4S)-3-(carboxymethyl)-4-prop-1-en-2-ylpyrrolidine-2-carboxylic acid;hydrate
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Molecular Formula:
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C10H15NO4 H2O |
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Molecular Weight: |
231.2
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CAS Number
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58002-62-3
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Purity:
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≥98%
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Storage Conditions:
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Product should be kept at -20°C.
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References:
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Coyle, J. T., & Schwarcz, R. (1976). Lesion of striatal neurons with kainic acid provides a model for Huntington's chorea. Lothman, E. W., & Collins, R. C. (1981). Kainic acid induced limbic seizures: metabolic, behavioral, electroencephalographic and neuropathological correlates. Brain research, 218(1), 299-318. Olney, J. W., Rhee, V., & Ho, O. L. (1974). Kainic acid: a powerful neurotoxic analogue of glutamate. Brain research, 77(3), 507-512. |