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Ionomycin Calcium Salt



Catalog Number : 5608212

Description

Ionomycin is an ionphore discovered in Streptomyces conglobatus and used in the study of intracellular calcium. It is also reported to stimulate the intracellular production of IL-2, IL-4 and perforin. It is supplied as a a calcium salt for ease of storage.
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Additional Information

Applications:
FA
Synonyms:
IONOMYCINCALCIUMSALT
Formulation:
Crystalline solid
Chemical Name:
calcium;(4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-19,21-dihydroxy-22-[(2S,5S)-5-[(2R,5S)-5-[(1R)-1-hydroxyethyl]-5-methyloxolan-2-yl]-5-methyloxolan-2-yl]-4,6,8,12,14,18,20-heptamethyl-11-oxido-9-oxodocosa-10,16-dienoate
Molecular Formula:

C41H70O9 Ca

Molecular Weight:
747.1
CAS Number
56092-82-1
Purity:
≥98%
Storage Conditions:
Product should be kept at -20°C.
References:

Liu, C. M., & Hermann, T. E. (1978). Characterization of ionomycin as a calcium ionophore. Journal of Biological Chemistry253(17), 5892-5894.

Morgan, A. J., & Jacob, R. (1994). Ionomycin enhances Ca2+ influx by stimulating store-regulated cation entry and not by a direct action at the plasma membrane. Biochem. J300, 665-672.

Elzi, D. J., Bjornsen, A. J., MacKenzie, T., Wyman, T. H., & Silliman, C. C. (2001). Ionomycin causes activation of p38 and p42/44 mitogen-activated protein kinases in human neutrophils. American Journal of Physiology-Cell Physiology281(1), C350-C360.


Availability: In stock

Size Price Qty
1mg
$20.00
10mg
$135.00