ID-8
Catalog Number : 1474669
description
ID-8 inhibits tyrosine phosphorylation-regulated kinases and is used to maintain the pluripotency and sustain self-renewal of mouse embryonic stem cells. It is also reported to stimulate proliferation and enhance Wnt-mediated human embryonic cell survival
Additional Information
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Applications:
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FA
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Synonyms:
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ID 8, 1-(4-Methoxyphenyl)-2-methyl-3-nitro-1H-indol-6-ol, AC1LGAMV, HY-15838
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Formulation:
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Crystalline solid
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Chemical Name:
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1-(4-methoxyphenyl)-2-methyl-3-nitroindol-6-ol
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Molecular Formula:
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C16H14N2O4 |
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Molecular Weight: |
298.3
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CAS Number
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147591-46-6
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Purity:
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≥98%
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Storage Conditions:
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Product should be kept at -20°C.
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References:
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Kochegarov, A. (2009). Small molecules for stem cells. Hasegawa, K., Yasuda, S. Y., Teo, J. L., Nguyen, C., McMillan, M., Hsieh, C. L., ... & Kahn, M. (2012). Wnt signaling orchestration with a small molecule DYRK inhibitor provides long-term xeno-free human pluripotent cell expansion.Stem cells translational medicine, 1(1), 18-28. Miyabayashi, T., Yamamoto, M., Sato, A., Sakano, S., & Takahashi, Y. (2008). Indole derivatives sustain embryonic stem cell self-renewal in long-term culture. Bioscience, biotechnology, and biochemistry, 72(5), 1242-1248. |