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Gastrin I



Catalog Number : 1003377

Description

Gastrin is a peptide hormone that is a major physiological regulator of gastric acid section and a promoter of gastric mucosal growth. It binds to cholecystokinin B receptors (CCKBR) and stimulates an increase in intracellular CA++, the production of inositol phosphate, and the activation of protein kinase C. Gastrin is also involved in gastric epithelial cell proliferation and maturation and is utilized in gastrointestinal organoids research.
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Additional Information

Applications:
FA
Synonyms:
GAS, GAST
Formulation:
Crystalline solid
Chemical Name:
H-Glp-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2
Molecular Formula:

C97H124N20O31S

Molecular Weight:
2098.2
CAS Number
10047-33-3
Purity:
≥95%
Storage Conditions:
Product should be kept at -20°C.
References:

Noble, F., Wank, S. A., Crawley, J. N., Bradwejn, J., Seroogy, K. B., Hamon, M., & Roques, B. P. (1999). International Union of Pharmacology. XXI. Structure, distribution, and functions of cholecystokinin receptors. Pharmacological Reviews51(4), 745-781.

Lee, Y., Urbanska, A. M., Hayakawa, Y., Wang, H., Au, A. S., Luna, A. M., ... & Friedman, R. A. (2017). Gastrin stimulates a cholecystokinin-2-receptor-expressing cardia progenitor cell and promotes progression of Barrett's-like esophagus. Oncotarget8(1), 203.

Fatehullah, A., Tan, S. H., & Barker, N. (2016). Organoids as an in vitro model of human development and disease. Nature cell biology18(3), 246.


Availability: In stock

Size Price Qty
1mg
$250.00