Anti-Human/Mouse CD62P (P-Selectin) SAFIRE Purified

Grouped product items
SizePrice Qty
50ug
$130.00
500ug
$350.00

Additional Psel.KO2.12 Formats

Cat.No.FormatStarting From
04722-25SAFIRE Purified$ 130.00
Catalog Number : 04722-25

description

The Psel.KO2.12 monoclonal antibody specifically reacts with mouse CD62P (P-Selectin), a 140 kDA type I transmembrane glycoprotein also known as granule membrane protein 140 (GMP-140). Upon activation it is quickly transported to the plasma membrane from the alpha-granules of platelets and WEibel-Palade bodies of endothelial cells. It is essential to the functions of cell adhesion during inflammatory reactions and in the interaction of platelets with monocytes and neutrophils. The Psel.KO2.12 antibody binds to an epitope common to several species including mouse, human, and rat.

Additional Information

Clone:
Psel.KO2.12
Format:
SAFIRE Purified
Applications:
FC, FA
Reactivity:
Human, Mouse
Isotype:
Mouse IgG1
Research Interest:Adaptive Immunity, Angiogenesis
Application:FC, FA
Clone:Psel.KO2.12
Preparation:
The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography.
Formulation:
Phosphate-buffered aqueous solution, ph7.2.
References:

Massaguer, A., Engel, P., Pérez‐del‐Pulgar, S., Bosch, J., & Pizcueta, P. (2000). Production and characterization of monoclonal antibodies against conserved epitopes of P‐selectin (CD62P). Tissue antigens56(2), 117-128.

Kansas, G. S. (1996). Selectins and their ligands: current concepts and controversies. Blood88(9), 3259-3287.

Bullard, D. C., Kunkel, E. J., Kubo, H., Hicks, M. J., Lorenzo, I., Doyle, N. A., ... & Beaudet, A. L. (1996). Infectious susceptibility and severe deficiency of leukocyte rolling and recruitment in E-selectin and P-selectin double mutant mice. The Journal of experimental medicine183(5), 2329-2336.

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