Anti-Mouse IL-1 beta SAFIRE Purified

Grouped product items
Size Price Qty
50ug
$100.00
500ug
$310.00

Additional B122 Formats

Cat.No. Format Starting From
82212-25 SAFIRE Purified $ 100.00
Catalog Number : 82212-25

description

The B122 monoclonal antibody specifically reacts with the precursor and mature secreted forms of mouse IL-1β and is cross-reactive with rat IL-1β. IL-1α and IL-1β are recognized by the same cell surface receptor but are generated from distinct genes. The B122 antibody is reported to neutralize the bioactivity of natural or recombinant IL-1β.

Additional Information

Clone:
B122
Format:
SAFIRE Purified
Applications:
FA, Neutralization
Reactivity:
Mouse, Rat
Isotype:
Armenian Hamster IgG
Research Interest: Innate Immunity
Cell Type: Macrophage / Monocyte
Application: FA, Neutralization
Clone: B122
Preparation:
The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography.
Formulation:
Phosphate-buffered aqueous solution, ph7.2.
References:

Hogquist, K. A., Nett, M. A., Sheehan, K. C., Pendleton, K. D., Schreiber, R. D., & Chaplin, D. D. (1991). Generation of monoclonal antibodies to murine IL-1 beta and demonstration of IL-1 in vivo. The Journal of immunology146(5), 1534-1540.

Fei, R., Gott, K., Edwards, B., & Schuyler, M. (1995). Experimental hypersensitivity pneumonitis: in vitro effects of interleukin-2 and interferon-gamma. The Journal of laboratory and clinical medicine126(5), 485-494.

Miller, B. E., Krasney, P. A., Gauvin, D. M., Holbrook, K. B., Koonz, D. J., Abruzzese, R. V., ... & Ator, M. A. (1995). Inhibition of mature IL-1 beta production in murine macrophages and a murine model of inflammation by WIN 67694, an inhibitor of IL-1 beta converting enzyme. The Journal of Immunology,154(3), 1331-1338.

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