Anti-Mouse CD20 SAFIRE Purified

Grouped product items
SizePrice Qty
100 ug
$140.00
500 ug
$470.00

Additional AISB12 Formats

Cat.No.FormatStarting From
02312-25SAFIRE Purified$ 140.00
Catalog Number : 02312-25

description

The AISB12 monoclonal antibody specifically reacts with mouse cd20, a 32kDA B-lymphocyte surface molecule. CD20 is expressed by B cells in all stage of development, except for the initial pro-B and final plasma cells. CD20 has no natural ligands and has an important role in enabling B cells to respond optimally to T-independent antigens. The AISB12 antibody binds to the extracellular loop domain of the CD20 molecule.

Additional Information

Clone:
AISB12
Format:
SAFIRE Purified
Applications:
FC, FA
Reactivity:
Mouse
Isotype:
Rat IgG2a
Research Interest:Adaptive Immunity
Cell Type:B Cells
Application:FC, FA
Clone:AISB12
Preparation:
The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Formulation:
Phosphate-buffered aqueous solution, ph7.2.
References:

Uchida, J., Hamaguchi, Y., Oliver, J. A., Ravetch, J. V., Poe, J. C., Haas, K. M., & Tedder, T. F. (2004). The innate mononuclear phagocyte network depletes B lymphocytes through Fc receptor–dependent mechanisms during anti-CD20 antibody immunotherapy. The Journal of experimental medicine,199(12), 1659-1669.

Uchida, J., Lee, Y., Hasegawa, M., Liang, Y., Bradney, A., Oliver, J. A., ... & Tedder, T. F. (2004). Mouse CD20 expression and function. International immunology16(1), 119-129.

Qian, J., Zheng, Y., Zheng, C., Wang, L., Qin, H., Hong, S., ... & Yi, Q. (2012). Active vaccination with Dickkopf-1 induces protective and therapeutic antitumor immunity in murine multiple myeloma. Blood119(1), 161-169.

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