Anti-Mouse CD1d SAFIRE Purified

Grouped product items
Size	Price	Qty
100 ug	$280.00
500 ug	$565.00

Additional 1B1 Formats

Cat.No.	Format	Starting From
03112-25	SAFIRE Purified	$ 280.00

Catalog Number : 03112-25

description

The 1B1 monoclonal antibody specifically reacts with mouse CD1d, a 48kDA type I membrane glycoprotein with a structural homology to MHC class I molecules. CD1d is expressed by mouse leukocytes, epithelial cells, thymocytes, and dendritic cells and is the only molecules in the CD1 family to have been found in the mouse. The 1B1 antibody detects CD1d in association with the Beta2m molecule.

Additional Information

Clone:	1B1
Format:	SAFIRE Purified
Applications:	FC, FA
Reactivity:	Mouse
Isotype:	Rat IgG2b, kappa
Research Interest:	Innate Immunity
Cell Type:	Dendritic Cells
Application:	FC, FA
Clone:	1B1
Preparation:	The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Formulation:	Phosphate-buffered aqueous solution, ph7.2.
References:	Szalay, G., Ladel, C. H., Blum, C., Brossay, L., Kronenberg, M., & Kaufmann, S. H. (1999). Cutting edge: anti-CD1 monoclonal antibody treatment reverses the production patterns of TGF-β2 and Th1 cytokines and ameliorates listeriosis in mice. The Journal of Immunology, 162(12), 6955-6958. Roark, J. H., Park, S. H., Jayawardena, J., Kavita, U., Shannon, M., & Bendelac, A. (1998). CD1. 1 expression by mouse antigen-presenting cells and marginal zone B cells. The Journal of Immunology, 160(7), 3121-3127. Amano, M., Baumgarth, N., Dick, M. D., Brossay, L., Kronenberg, M., Herzenberg, L. A., & Strober, S. (1998). CD1 expression defines subsets of follicular and marginal zone B cells in the spleen: β2-microglobulin-dependent and independent forms. The Journal of Immunology, 161(4), 1710-1717.