Anti-Mouse CD180 (RP-105) SAFIRE Purified

Grouped product items
SizePrice Qty
50ug
$145.00
100ug
$240.00

Additional RP/14 Formats

Cat.No.FormatStarting From
12912-25SAFIRE Purified$ 145.00
Catalog Number : 12912-25

description

The RP/14 monoclonal antibody binds to mouse CD180, a 105kDA cell surface molecule consisting of extracellular leucine rich repeats (LCC) and a short cytoplasmic tail also known as Bgp-95 and RP105. CD180 is expressed on B cells, dendritic cells, monocytes, and macrophages. It forms a cell surface receptor complex with MD-1 and with TLR4 is involved with the recognition of bacterial lipopolysaccharide (LPS).

Additional Information

Clone:
RP/14
Format:
SAFIRE Purified
Applications:
FC, FA
Reactivity:
Mouse
Isotype:
Rat IgG2a, kappa
Research Interest:Innate Immunity, Apoptosis
Cell Type:B Cells, Macrophage / Monocyte, Dendritic Cells
Application:FC, FA
Clone:RP/14
Preparation:
The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography.
Formulation:
Phosphate-buffered aqueous solution, ph7.2.
References:

Miyake, K., Shimazu, R., Kondo, J., Niki, T., Akashi, S., Ogata, H., ... & Kimoto, M. (1998). Mouse MD-1, a molecule that is physically associated with RP105 and positively regulates its expression. The Journal of Immunology,161(3), 1348-1353.

Miyake, K., Yamashita, Y., Ogata, M., Sudo, T., & Kimoto, M. (1995). RP105, a novel B cell surface molecule implicated in B cell activation, is a member of the leucine-rich repeat protein family. The Journal of Immunology154(7), 3333-3340.

Chan, V. W., Mecklenbräuker, I., Su, I. H., Texido, G., Leitges, M., Carsetti, R., ... & Tarakhovsky, A. (1998). The molecular mechanism of B cell activation by toll-like receptor protein RP-105. The Journal of experimental medicine,188(1), 93-101.

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