Anti-Mouse CD103 (Integrin alpha E) SAFIRE Purified

Grouped product items
SizePrice Qty
100 ug
$210.00

Additional 2E7 Formats

Cat.No.FormatStarting From
15112-25SAFIRE Purified$ 210.00
15112-80APC$ 110.00
Catalog Number : 15112-25

description

The 2E7 monoclonal antibody specifically reacts with mouse CD103, a type I transmembrane glycoprotein in the integrin family that bind to E-cadherin. CD103 is expressed on intraepithelial lymphocyte T cells, peripheral regulatory T cells, lamina propria T cells, and a subset of dendritic cells. It is reported to be involved in T cell homing and immune system regulation.

Additional Information

Clone:
2E7
Format:
SAFIRE Purified
Applications:
FC, FA
Reactivity:
Mouse
Isotype:
Armenian Hamster IgG
Research Interest:Adaptive Immunity
Cell Type:Dendritic Cells, T Cells, T Regulatory Cells
Application:FC, FA
Clone:2E7
Preparation:
The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography.
Formulation:
Phosphate-buffered aqueous solution, ph7.2.
References:

Hadley, G. A., Bartlett, S. T., Via, C. S., Rostapshova, E. A., & Moainie, S. (1997). The epithelial cell-specific integrin, CD103 (alpha E integrin), defines a novel subset of alloreactive CD8+ CTL. The Journal of Immunology159(8), 3748-3756.

Schön, M. P., Schön, M., Parker, C. M., & Williams, I. R. (2002). Dendritic Epidermal T Cells (DETC) are Diminished in Integrin &agr; E (CD103)-Deficient Mice. Journal of investigative dermatology119(1), 190-193.

Zikri, N. N., Schumer, E., Wang, J. J., Gaughan, A., Hadley, G. A., & Moffatt-Bruce, S. D. (2010). Induction of CD4< sup>+</sup> CD25< sup>+</sup> T Regulatory Cells with CD103 Depletion. Journal of Surgical Research163(1), 162-168.

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