Anti-Human IFN gamma SAFIRE Purified
Additional NIB42 Formats
| Cat.No. | Format | Starting From |
|---|---|---|
| 80821-25 | SAFIRE Purified | $ 160.00 |
Catalog Number : 80821-25
description
The NIB42 monoclonal antibody specifically reacts with human interferon gamma, a multifunctional cytokine that is produced mainly by activated T and NK cells. Interferon gamma has anti-viral and anti-parasitic properties and plays an important role in the activation, growth, and differentiation of macrophages, B and T lymphocytes, and natural killer cells. It interacts synergically with other cytokines, such as TNF-α, to inhibit proliferation of normal and transformed cells. The NIB42 antibody neutralizes IFN-γ.
Additional Information
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Clone:
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NIB42
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Format:
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SAFIRE Purified
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Applications:
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FC, Neutralization,
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Reactivity:
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Human
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Isotype:
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Mouse IgG1, kappa
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| Research Interest: | Innate Immunity, Adaptive Immunity, Cytokines & Growth Factors |
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| Cell Type: | Th1 cells, NK and NKT Cells, T Cells |
| Application: | FC, Neutralization, |
| Clone: | NIB42 |
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Preparation:
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The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
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Formulation:
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Phosphate-buffered aqueous solution, ph7.2.
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References:
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Meager, A. (1987). Antibodies against interferons: Characterization of interferons and immunoassays. Lymphockies and Interferons. A Practical Approach. Clemens, MJ, AG Morris, and AJH Gearing, eds. IRL Press Ltd. Oxford, 105. Meager, A., Parti, S., Barwick, S., Spragg, J., & O'hagan, K. (1984). Detection of hybridomas secreting monoclonal antibodies to human gamma interferon using a rapid screening technique and specificity of certain monoclonal antibodies to gamma interferon. Journal of interferon research, 4(4), 619-625. |