Anti-Human gamma delta TCR SAFIRE Purified

Grouped product items
SizePrice Qty
50 ug
$130.00

Additional B1.1 Formats

Cat.No.FormatStarting From
81311-25SAFIRE Purified$ 130.00
Catalog Number : 81311-25

description

The B1.1 monoclonal antibody specifically reacts with the gamma delta T cell receptor, a receptor complex composed of the two disulfide linked transmembrane glycoproteins. The complex is expressed on peripheral T cell subsets and thymocytes and is reported to be involved in the recognition of tumor and bacterial antigens. Research is being conducted to determine its role in antigen presentation and autoimmune response regulation.

Additional Information

Clone:
B1.1
Format:
SAFIRE Purified
Applications:
FC, FA
Reactivity:
Human
Isotype:
Mouse IgG1, kappa
Research Interest:Adaptive Immunity, Innate Immunity
Cell Type:T Cells
Application:FC, FA
Clone:B1.1
Preparation:
The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography.
Formulation:
Phosphate-buffered aqueous solution, ph7.2.
References:

Bonneville, M., O'Brien, R. L., & Born, W. K. (2010). γδ T cell effector functions: a blend of innate programming and acquired plasticity. Nature Reviews Immunology10(7), 467-478.

De Libero, G. (1997). Sentinel function of broadly reactive human γδ T cells.Immunology today18(1), 22-26.

Stinissen, P., Vandevyver, C., Medaer, R., Vandegaer, L., Nies, J., Tuyls, L., ... & Zhang, J. (1995). Increased frequency of gamma delta T cells in cerebrospinal fluid and peripheral blood of patients with multiple sclerosis. Reactivity, cytotoxicity, and T cell receptor V gene rearrangements. The Journal of Immunology154(9), 4883-4894.

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