Anti-Human CD95 (APO-1/Fas) SAFIRE Purified
Additional EOS9.1 Formats
| Cat.No. | Format | Starting From |
|---|---|---|
| 08011-25 | SAFIRE Purified | $ 185.00 |
Catalog Number : 08011-25
description
The EOS9.1 monoclonal antibody specifically reacts with human CD95, a 45 kDA type I membrane molecule. CD95 is a member of the tumor necrosis factor receptor (TNF-R) family and is involved in the mechanisms that lead to cellular apoptosis. It is expressed on fibroblasts, monocytes, lymphocytes, and neutrophils. CD95 induces apoptosis after binding with CD178 or Fas ligand and the EOS9.1 antibody is reported to be used for inducing apoptosis in Fas-positive cells.
Additional Information
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Clone:
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EOS9.1
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Format:
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SAFIRE Purified
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Applications:
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FC, FA
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Reactivity:
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Human
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Isotype:
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Mouse IgM, kappa
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| Cell Type: | T Cells, Macrophage / Monocyte, B Cells, NK and NKT Cells |
|---|---|
| Application: | FC, FA |
| Clone: | EOS9.1 |
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Preparation:
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The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
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Formulation:
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Phosphate-buffered aqueous solution, ph7.2.
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References:
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Nagata, S., & Golstein, P. (1995). The Fas death factor. Science, 267(5203), 1449-1456. Leucocyte Typing VI: White Cell Differentiation Antigens: Proceedings of the Sixth International Workshop and Conference Held in Kobe, Japan, 10-14 November 1996. Garland Pub., 1998. Zhang, P., Sun, D., Ke, Y., Kaplan, H. J., & Shao, H. (2007). The net effect of costimulatory blockers is dependent on the subset and activation status of the autoreactive T cells. The Journal of Immunology, 178(1), 474-479. |