Anti-Human CD3 SAFIRE Purified

Grouped product items
Size Price Qty
100 μg
$160.00
500 μg
$295.00

Additional OKT3 Formats

Cat.No. Format Starting From
05121-20 Purified $ 115.00
05121-25 SAFIRE Purified $ 160.00
05121-40 BG Violet 450 $ 95.00
05121-60 PE $ 50.00
05121-80 APC $ 65.00
05121-50 FITC $ 40.00
05121-70 PerCP-Cyanine5.5 $ 135.00
05121-77 PE-Cyanine7 $ 95.00
Catalog Number : 05121-25

description

The OKT3 monoclonal antibody specifically reacts with the ε chain of the CD3/T lymphocyte antigen receptor complex. The CD3 complex contains γ, δ, and ε chains, and it is part of the TCR complex, expressed by all mature T lymphocytes and by the thymocyte lineage. CD3 enhances the antigen recognition by signal transduction.

The OKT3 antibody is an immunosuppressive, which has proven to be an effective therapeutic agent in liver, heart, and renal allograft rejection.

Additional Information

Clone:
OKT3
Format:
SAFIRE Purified
Applications:
FC, FA, IHC
Reactivity:
Human
Isotype:
Mouse IgG2a, kappa
Research Interest: Adaptive Immunity
Cell Type: NK and NKT Cells, T Cells, T Regulatory Cells, Th17 cells
Application: FC, FA, IHC
Clone: OKT3
Preparation:
The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Formulation:
Phosphate-buffered aqueous solution, ph7.2.
References:

Schlossman, S., L. Bloumsell, et al. eds (1995). Leucocyte Typing V: White Cell Differentiation Antigens. Oxford University Press. New York

Knapp W (1989) Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.

Adair, J. R., Athwal, D. S., Bodmer, M. W., Bright, S. M., Collins, A. M., Pulito, V. L., ... & Jolliffe, L. K. (1994). Humanization of the murine anti-human CD3 monoclonal antibody OKT3. Human Antibodies5(1), 41-47.

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