Anti-Mouse CD117 (c-Kit) Purified

Grouped product items
SizePrice Qty
100 μg
$115.00

Additional ACK2 Formats

Cat.No.FormatStarting From
19112-60PE$ 50.00
19112-20Purified$ 115.00
19112-25SAFIRE Purified$ 135.00
19112-80APC$ 70.00
19112-77PE-Cyanine7$ 65.00
Catalog Number : 19112-20

description

The ACK2 monoclonal antibody specifically reacts with mouse CD117 (c-Kit receptor), a 145 kDa transmembrane tyrosine-kinase receptor encoded by the Kit gene. The c-Kit receptor, also known as stem cell factor receptor, is expressed on hematopoietic progenitor cells in adult bone marrow, in progenitors of erythroid and myeloid lineages, and precursors of B and T cells. CD117 enhances the proliferation and the differentiation of the hematopoietic progenitor cells and seems to enhance the development of T cells, as the c-Kit receptor and its ligand are expressed by the thymus.

Additional Information

Clone:
ACK2
Format:
Purified
Applications:
FC, FA, IHC, ICC, WB
Reactivity:
Mouse
Isotype:
Rat IgG2b, kappa
Research Interest:Angiogenesis
Application:FC, FA, IHC, ICC, WB
Clone:ACK2
Preparation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Godfrey, D. I., Kennedy, J., Mombaerts, P., Tonegawa, S., & Zlotnik, A. (1994). Onset of TCR-beta gene rearrangement and role of TCR-beta expression during CD3-CD4-CD8-thymocyte differentiation. The Journal of Immunology152(10), 4783-4792.

Godfrey, D. I., Zlotnik, A. L. B. E. R. T., & Suda, T. A. K. A. S. H. I. (1992). Phenotypic and functional characterization of c-kit expression during intrathymic T cell development. The Journal of Immunology149(7), 2281-2285.

Feng, H., Sandlow, J. I., & Sandra, A. (1998). The c-kit receptor and its possible signaling transduction pathway in mouse spermatozoa. Molecular reproduction and development49(3), 317-326.

© BioGems International, Inc. All rights reserved.