Anti-Human Foxp1 Purified

Grouped product items
Size Price Qty
100 ug
$290.00

Additional JC12 Formats

Cat.No. Format Starting From
83011-20 Purified $ 290.00
Catalog Number : 83011-20

description

The JC12 monoclonal antibody specifically reacts with human Foxp1, a winged helix transcription factor that is expressed in almost all human tissue. In several tumor types, the gene is lost suggesting it plays a tumor suppressive role. It plays an important role in the development of the brain, lungs, thymus, and heart. Foxp1 is also involved in the development of early B cells.

Additional Information

Clone:
JC12
Format:
Purified
Applications:
FC, IHC, WB,
Reactivity:
Human
Isotype:
Mouse IgG2a, kappa
Research Interest: Adaptive Immunity
Cell Type: B Cells
Application: FC, IHC, WB,
Clone: JC12
Preparation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Banham, A. H., Beasley, N., Campo, E., Fernandez, P. L., Fidler, C., Gatter, K., ... & Cordell, J. L. (2001). The FOXP1 winged helix transcription factor is a novel candidate tumor suppressor gene on chromosome 3p. Cancer research,61(24), 8820-8829.

Banham, A. H., Connors, J. M., Brown, P. J., Cordell, J. L., Ott, G., Sreenivasan, G., ... & Gascoyne, R. D. (2005). Expression of the FOXP1 transcription factor is strongly associated with inferior survival in patients with diffuse large B-cell lymphoma. Clinical Cancer Research11(3), 1065-1072.

Arber, S. (2008). FoxP1: conducting the Hox symphony in spinal motor neurons. Nature neuroscience11(10), 1122-1124.

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