Anti-Human CD93 PE
Catalog Number : 06011-60
description
The R3 monoclonal antibody specifically reacts with Human CD93, a glycoprotein that binds to C1q and is also known as C1qRp. Cd93 is highly express on monocytes and macrophages, but not on B and T cells and is involved in phagocytosis, migration, and adhesion. It is reported to be used to define a stem cell population with hematopoietic potential.
Additional Information
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Clone:
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R3
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Format:
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PE
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Applications:
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FC
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Reactivity:
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Human
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Isotype:
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Mouse IgM
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| Research Interest: | Stem Cell Research |
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| Cell Type: | Macrophage / Monocyte |
| Application: | FC |
| Clone: | R3 |
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Preparation:
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The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
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Formulation:
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Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
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References:
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Bohlson, S. S., Silva, R., Fonseca, M. I., & Tenner, A. J. (2005). CD93 is rapidly shed from the surface of human myeloid cells and the soluble form is detected in human plasma. The Journal of Immunology, 175(2), 1239-1247. Bohlson, S. S., Zhang, M., Ortiz, C. E., & Tenner, A. J. (2005). CD93 interacts with the PDZ domain-containing adaptor protein GIPC: implications in the modulation of phagocytosis. Journal of leukocyte biology, 77(1), 80-89. Greenlee, M. C., Sullivan, S. A., & Bohlson, S. S. (2008). CD93 and related family members: their role in innate immunity. Current drug targets, 9(2), 130-138. |