Anti-Human CD8a Purified

Grouped product items
Size Price Qty
100 μg
$90.00

Additional RPA-T8 Formats

Cat.No. Format Starting From
10131-20 Purified $ 90.00
10131-77 PE-Cyanine7 $ 85.00
10131-40 BG Violet 450 $ 85.00
10131-50 FITC $ 45.00
10131-87 APC-Cyanine7 $ 115.00
10131-80 APC $ 70.00
10131-60 PE $ 50.00
10131-70 PerCP-Cyanine5.5 $ 90.00
10131-30 Biotin $ 65.00
10131-45 BG Violet 500 $ 110.00
Catalog Number : 10131-20

description

The RPA-T8 monoclonal antibody specifically reacts with the human CD8a molecule, a 32 kDa cell surface receptor expressed either as a heterodimer (CD8 α/β) or as a homodimer (CD8 α/α) on the majority of thymocytes, a subpopulation of mature T cells, and natural killer cells. CD8 interacts with the major histocompatibility complex class I (MHC class I) molecules on antigen-presenting cells or epithelial cells. The RPA-T8 antibody reacts with 13-48% of peripheral lymphocytes, 80% of thymocytes, and a subset of natural killer cells.

RPA-T8, OKT8, and HIT8a antibodies do not compete with each other for binding to peripheral leukocytes, meaning that that they do not recognize the same epitope or block each other by steric hindrance.

Additional Information

Clone:
RPA-T8
Format:
Purified
Applications:
FC, FA, IHC, IP
Reactivity:
Human
Isotype:
Mouse IgG1, kappa
Research Interest: Adaptive Immunity
Cell Type: NK and NKT Cells, T Cells
Application: FC, FA, IHC, IP
Clone: RPA-T8
Preparation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Knapp W (1989) Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.

Schlossman, S., L. Bloumsell, et al. eds (1995). Leucocyte Typing V: White Cell Differentiation Antigens. Oxford University Press. New York

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