Anti-Human CD45 Purified

Grouped product items
Size Price Qty
100 μg
$75.00

Additional HI30 Formats

Cat.No. Format Starting From
07111-40 BG Violet 450 $ 120.00
07111-20 Purified $ 75.00
07111-50 FITC $ 55.00
07111-87 APC-Cyanine7 $ 120.00
07111-80 APC $ 85.00
07111-60 PE $ 80.00
07111-77 PE-Cyanine7 $ 120.00
07111-70 PerCP-Cyanine5.5 $ 120.00
07111-30 Biotin $ 65.00
07111-45 BG Violet 500 $ 110.00
Catalog Number : 07111-20

description

The HI30 monoclonal antibody specifically reacts with the 180 kDa, 190 kDa, 205 kDa, and 220 kDa isoforms of the human leukocyte common antigen (LCA) CD45. It is expressed on lymphocytes, granulocytes, monocytes, thymocytes, and eosinophils, but not on mature erythrocytes, platelets, mature erythroid cells of bone marrow, and non-hematopoietic tissues. CD45 is essential for T cell activation and the tyrosine phosphatase activity of its intracellular region is integral for signal transduction.

Additional Information

Clone:
HI30
Format:
Purified
Applications:
FC, FA, IHC, ICC, IP, WB
Reactivity:
Human
Isotype:
Mouse IgG1, kappa
Research Interest: Adaptive Immunity
Cell Type: T Cells, B Cells, Macrophage / Monocyte, NK and NKT Cells
Application: FC, FA, IHC, ICC, IP, WB
Clone: HI30
Preparation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Knapp W (1989) Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.

Ninomiya, M., Abe, A., Katsumi, A., Xu, J., Ito, M., Arai, F., ... & Naoe, T. (2006). Homing, proliferation and survival sites of human leukemia cells in vivo in immunodeficient mice. Leukemia21(1), 136-142.

Yoshino, N., AMI, Y., TERAO, K., TASHIRO, F., & HONDA, M. (2000). Upgrading of flow cytometric analysis for absolute counts, cytokines and other antigenic molecules of cynomolgus monkeys (Macaca fascicularis) by using anti-human cross-reactive antibodies. Experimental Animals49(2), 97-110.

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