Anti-Human CD20 Purified

Grouped product items
SizePrice Qty
25 ug
$55.00
100 ug
$110.00

Additional 2H7 Formats

Cat.No.FormatStarting From
02311-80APC$ 135.00
02311-20Purified$ 55.00
02311-60PE$ 100.00
02311-40BG Violet 450$ 120.00
02311-50FITC$ 70.00
02311-87APC-Cyanine7 $ 135.00
02311-70PerCP-Cyanine5.5 $ 160.00
02311-77PE-Cyanine7$ 140.00
02311-30Biotin$ 80.00
Catalog Number : 02311-20

description

The 2H7 monoclonal antibody specifically reacts with human CD20, a 33-37kDA B-lymphocyte surface molecule. CD20 is an unglycosylated four-transmembrane phosphoprotein expressed by B cells in all stage of development, except the final plasma cells. It has been reported that the molecule is involved in B cell activation and has also been observed on a subset of circulating T lymphocytes.

Additional Information

Clone:
2H7
Format:
Purified
Applications:
FC, IHC
Reactivity:
Human
Isotype:
Mouse IgG2b, kappa
Research Interest:Adaptive Immunity
Cell Type:B Cells
Application:FC, IHC
Clone:2H7
Preparation:
The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.

Polyak, M. J., & Deans, J. P. (2002). Alanine-170 and proline-172 are critical determinants for extracellular CD20 epitopes; heterogeneity in the fine specificity of CD20 monoclonal antibodies is defined by additional requirements imposed by both amino acid sequence and quaternary structure. Blood99(9), 3256-3262.

Schlossman, S. F. (1995). Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press.

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