Anti-Human CD1a Purified
Catalog Number : 03111-20
description
The HI149 monoclonal antibody specifically reacts with human CD1a, a 49kDA type I membrane glycoprotein. It is expressed on dendritic cells, Langerhans cells, and cortical thymocytes. CD1a plays a role in antigen presentation and ,like MHC Class I, it non-covalently associates with Beta2-microglobulin.
Additional Information
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Clone:
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HI149
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Format:
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Purified
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Applications:
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FC, IHC
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Reactivity:
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Human
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Isotype:
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Mouse IgG1, kappa
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| Research Interest: | Adaptive Immunity, Innate Immunity |
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| Cell Type: | T Cells, Dendritic Cells |
| Application: | FC, IHC |
| Clone: | HI149 |
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Preparation:
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The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
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Formulation:
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Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
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References:
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Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989. Schlossman, S. F. (1995). Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press. Hanau, D., Schmitt, D. A., Bieber, T., Schmitt, D., & Cazenave, J. P. (1990). Possible mechanism of action of CD1a antigens. Journal of investigative dermatology, 95(5), 503-505. |