Anti-Human CD144 (VE-Cadherin) Purified
description
The 16B1 monoclonal antibody specifically reacts with human CD144, the 140 kDA molecule called vascular endothelial (VE-cadherin) or cadherin 5. CD144 is an endothelial specific calcium-dependent adhesion molecule involved in cell contact-dependent growth inhibition, migration, survival, adhesion. It is concentrated at the intercellular boundaries of endothelial cells and essential in maintaining cell layer integrity.
Additional Information
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Clone:
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16B1
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Format:
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Purified
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Applications:
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FC, IHC, WB
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Reactivity:
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Human
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Isotype:
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Mouse IgG1
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| Research Interest: | Angiogenesis |
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| Cell Type: | Stem Cells |
| Application: | FC, IHC, WB |
| Clone: | 16B1 |
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Preparation:
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The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography.
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Formulation:
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Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
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References:
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Breviario, F., Caveda, L., Corada, M., Martin-Padura, I., Navarro, P., Golay, J., ... & Dejana, E. (1995). Functional properties of human vascular endothelial cadherin (7B4/cadherin-5), an endothelium-specific cadherin. Arteriosclerosis, thrombosis, and vascular biology, 15(8), 1229-1239. Rajesh, D., Chinnasamy, N., Mitalipov, S. M., Wolf, D. P., Slukvin, I., Thomson, J. A., & Shaaban, A. F. (2007). Differential requirements for hematopoietic commitment between human and rhesus embryonic stem cells. Stem Cells,25(2), 490-499. Dejana, E., Bazzoni, G., & Lampugnani, M. G. (1999). Vascular endothelial (VE)-cadherin: only an intercellular glue?. Experimental cell research, 252(1), 13-19. |