Anti-Rat CD45R (B220) FITC

Grouped product items
Size Price Qty
100 ug
$165.00

Additional HIS24 Formats

Cat.No. Format Starting From
07113-50 FITC $ 165.00
Catalog Number : 07113-50

description

The HIS24 monoclonal antibody specifically reacts with an isoform of the rat CD45 glycoprotein. CD45R/B220 is expressed on all the development stages of B cells to the exclusion of plasma cells. The CD45 molecule is a member of the Protein Tyrosine Phosphatase (PTP) family, because its intracellular region contains two PTP domains. The extracellular region’s variability is caused by different levels of glycosylation, and the splicing of the 4, 5, and 6 exons. The HIS24 antibody is useful as a marker for the identification of B-cell progenitors.

Additional Information

Clone:
HIS24
Format:
FITC
Applications:
FC
Reactivity:
Rat
Isotype:
mouse IgG2b, kappa
Research Interest: Adaptive Immunity
Cell Type: B Cells, T Cells
Application: FC
Clone: HIS24
Preparation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Hermans, M. H. A., Deenen, G. J., De Boer, N., Bo, W., Kroese, F. G. M., & Opstelten, D. (1997). Expression of HIS50 Ag: a rat homologue of mouse heat‐stable antigen and human CD24 on B lymphoid cells in the rat. Immunology,90(1), 14-22.

Kroese, F. G., Butcher, E. C., Lalor, P. A., Stall, A. M., & Herzenberg, L. A. (1990). The rat B cell system: The anatomical localization of flow cytometry‐defined B cell subpopulations. European journal of immunology20(7), 1527-1534.Kroese, F. G. M., Opstelten, D., Wubbena, A. S., Deenen, G. J., Aten, J., Schwander, E. H., ... & Nieuwenhuis, P. (1985). Monoclonal antibodies to rat B lymphocyte (sub-) populations. In Microenvironments in the Lymphoid System(pp. 81-89). Springer US.

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