Anti-Mouse CD8b PE
Catalog Number : 10132-60
description
The H35-17.2 monoclonal antibody specifically reacts the mouse cd8 beta, a 32 kDa chain also known as Ly-3 and Lyt-3. CD8 is a T cell surface antigen co-receptor that interacts with MHC class I molecules on antigen presenting cells. It is expressed as a heterodimer with the alpha cd8 chain. The H35-17.2 antibody blocks T cell-mediated cytolysis of allogeneic lymphoma cells.
Additional Information
|
Clone:
|
H35-17.2
|
|
Format:
|
PE
|
|
Applications:
|
FC
|
|
Reactivity:
|
Mouse
|
|
Isotype:
|
Rat IgG2b, kappa
|
| Research Interest: | Adaptive Immunity |
|---|---|
| Cell Type: | NK and NKT Cells, T Cells |
| Application: | FC |
| Clone: | H35-17.2 |
|
Preparation:
|
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
|
|
Formulation:
|
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
|
|
References:
|
Lefrancois, L. (1991). Phenotypic complexity of intraepithelial lymphocytes of the small intestine. The Journal of Immunology, 147(6), 1746-1751. Walker, I. D., Murray, B. J., Hogarth, P. M., Kelso, A., & McKenzie, I. F. (1984). Comparison of thymic and peripheral T cell Ly‐2/3 antigens. European journal of immunology, 14(10), 906-910. THOMA-USZYNSKI, S., LADEL, C., & KAUFMANN, S. (1997). Abscess formation in Listeria monocytogenes-infected γδ T cell deficient mouse mutants involves αβ T cells. Microbial pathogenesis, 22(2), 123-128. |