Anti-Mouse CD31 PE
Catalog Number : 03412-60
description
The 390 monoclonal antibody specifically reacts with mouse cd31, a 130-140 kDA type I transmembrane glycoprotein also known as platelet-endothelial cell adhesion molecule-1 (PECAM-1). CD31 is reported to bind to CD38 and is expressed on platelets, monocytes, granulocytes, and endothelial cells. It plays a role in angiogenesis, wound healing, cellular migration, and signal transduction.
Additional Information
Clone: | 390 |
Format: | PE |
Applications: | FC |
Reactivity: | Mouse |
Isotype: | Rat IgG2a, kappa |
| Research Interest: | Angiogenesis |
|---|---|
| Cell Type: | B Cells, T Cells, Macrophage / Monocyte, NK and NKT Cells |
| Application: | FC |
| Clone: | 390 |
Preparation: | The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product. |
Formulation: | Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2. |
References: | HORENSTEIN, A., STOCKINGER, H., Imhof, B., & MALAVASI, F. (1998). CD38 binding to human myeloid cells is mediated by mouse and human CD31.Biochem. J, 330, 1129-1135. Baldwin, H. S., Shen, H. M., Yan, H. C., DeLisser, H. M., Chung, A., Mickanin, C., ... & Albelda, S. M. (1994). Platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31): alternatively spliced, functionally distinct isoforms expressed during mammalian cardiovascular development. Development, 120(9), 2539-2553. DeLisser, H. M., Christofidou-Solomidou, M., Strieter, R. M., Burdick, M. D., Robinson, C. S., Wexler, R. S., ... & Albelda, S. M. (1997). Involvement of endothelial PECAM-1/CD31 in angiogenesis. The American journal of pathology, 151(3), 671. |