Anti-Mouse CD275 (B7-H2) PE

Grouped product items
SizePrice Qty
50ug
$150.00
100ug
$270.00

Additional HK5.3 Formats

Cat.No.FormatStarting From
27812-60PE$ 150.00
Catalog Number : 27812-60

description

The HK5.3 monoclonal antibody reacts with mouse CD275, also known as B7-H2, B7h, B7RP-1, and ICOS ligand. CD275 is expressed on b cells, macrophages, monocytes, and dendritic cells. It binds to the ICOS (CRP-1 or AILIM) receptor expressed on activated T cells and interacts with the T cell costimulation pathway.

Additional Information

Clone:
HK5.3
Format:
PE
Applications:
FC
Reactivity:
Mouse
Isotype:
Rat IgG2a, kappa
Research Interest:Adaptive Immunity
Cell Type:Macrophage / Monocyte, B Cells
Application:FC
Clone:HK5.3
Preparation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Vermaelen, K., & Pauwels, R. (2004). Accurate and simple discrimination of mouse pulmonary dendritic cell and macrophage populations by flow cytometry: methodology and new insights. Cytometry Part A: the journal of the International Society for Analytical Cytology61(2), 170-177.

Tsushima, F., Tanaka, K., Otsuki, N., Youngnak, P., Iwai, H., Omura, K., & Azuma, M. (2006). Predominant expression of B7-H1 and its immunoregulatory roles in oral squamous cell carcinoma. Oral oncology42(3), 268-274.

Sokolovska, A., Hem, S. L., & HogenEsch, H. (2007). Activation of dendritic cells and induction of CD4+ T cell differentiation by aluminum-containing adjuvants. Vaccine25(23), 4575-4585.

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