Anti-Mouse CD275 (B7-H2) PE
Catalog Number : 27812-60
description
The HK5.3 monoclonal antibody reacts with mouse CD275, also known as B7-H2, B7h, B7RP-1, and ICOS ligand. CD275 is expressed on b cells, macrophages, monocytes, and dendritic cells. It binds to the ICOS (CRP-1 or AILIM) receptor expressed on activated T cells and interacts with the T cell costimulation pathway.
Additional Information
Clone:
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HK5.3
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Format:
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PE
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Applications:
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FC
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Reactivity:
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Mouse
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Isotype:
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Rat IgG2a, kappa
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Research Interest: | Adaptive Immunity |
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Cell Type: | Macrophage / Monocyte, B Cells |
Application: | FC |
Clone: | HK5.3 |
Preparation:
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The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
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Formulation:
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Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
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References:
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Vermaelen, K., & Pauwels, R. (2004). Accurate and simple discrimination of mouse pulmonary dendritic cell and macrophage populations by flow cytometry: methodology and new insights. Cytometry Part A: the journal of the International Society for Analytical Cytology, 61(2), 170-177. Tsushima, F., Tanaka, K., Otsuki, N., Youngnak, P., Iwai, H., Omura, K., & Azuma, M. (2006). Predominant expression of B7-H1 and its immunoregulatory roles in oral squamous cell carcinoma. Oral oncology, 42(3), 268-274. Sokolovska, A., Hem, S. L., & HogenEsch, H. (2007). Activation of dendritic cells and induction of CD4+ T cell differentiation by aluminum-containing adjuvants. Vaccine, 25(23), 4575-4585. |