Anti-Mouse CD2 PE

Grouped product items
Size	Price	Qty
25 ug	$75.00
100 ug	$200.00

Additional RM2-5 Formats

Cat.No.	Format	Starting From
04112-60	PE	$ 75.00
04112-50	FITC	$ 55.00
04112-25	SAFIRE Purified	$ 145.00

Catalog Number : 04112-60

description

The RM2-5 monoclonal antibody specifically binds to mouse CD2, a member of the Ig superfamily and type I transmembrane glycoprotein. CD2 is expressed on B cells, T cells, NK cells, and thymocytes and its ligand is CD48. It may be involved in immunoregulation, thymocyte maturation, and T-cell activation. The RM2-5 antibody has been reported to block CD2 mediated cell to cell adhesion.

Additional Information

Clone:	RM2-5
Format:	PE
Applications:	FC
Reactivity:	Mouse
Isotype:	Rat IgG2b, lambda
Research Interest:	Adaptive Immunity
Cell Type:	B Cells, NK and NKT Cells, T Cells
Application:	FC
Clone:	RM2-5
Preparation:	The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:	Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:	Yagita, H., Nakamura, T., Karasuyama, H., & Okumura, K. (1989). Monoclonal antibodies specific for murine CD2 reveal its presence on B as well as T cells.Proceedings of the National Academy of Sciences, 86(2), 645-649. Nakamura, T. E. T. S. U. Y. A., Takahashi, K. A. Z. U. H. I. S. A., Fukazawa, T. O. H. R. U., Koyanagi, M. A. K. O. T. O., Yokoyama, A., Kato, H., ... & Okumura, K. (1990). Relative contribution of CD2 and LFA-1 to murine T and natural killer cell functions. The Journal of Immunology, 145(11), 3628-3634. Kato, K., Koyanagi, M., Okada, H., Takanashi, T., Wong, Y. W., Williams, A. F., ... & Yagita, H. (1992). CD48 is a counter-receptor for mouse CD2 and is involved in T cell activation. The Journal of experimental medicine, 176(5), 1241-1249.