Anti-Mouse CD184 (CXCR4) PE

Grouped product items
SizePrice Qty
50 ug
$170.00
100 ug
$290.00

Additional 2B11 Formats

Cat.No.FormatStarting From
16912-60PE$ 170.00
Catalog Number : 16912-60

description

The 2B11 monoclonal antibody specifically reacts with mouse CD184 (CXCR4or Fusin), a seven-transmembrane G-protein-coupled receptor. It is expressed by astrocytes, B cells, T cells, monocytes, neutrophils, neurons, and hematopoietic cell types. CD184 is a coreceptor for X4 HIV-1.

The monoclonal 2B11 antibody recognizes the amino terminus of CD184 and has functional activity.

Additional Information

Clone:
2B11
Format:
PE
Applications:
FC
Reactivity:
Mouse
Isotype:
Rat IgG2b, kappa
Research Interest:Stem Cell Research, Cytokines & Growth Factors
Cell Type:T Cells, Stem Cells
Application:FC
Clone:2B11
Preparation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Förster, R., Kremmer, E., Schubel, A., Breitfeld, D., Kleinschmidt, A., Nerl, C., ... & Lipp, M. (1998). Intracellular and surface expression of the HIV-1 coreceptor CXCR4/fusin on various leukocyte subsets: rapid internalization and recycling upon activation. The Journal of Immunology160(3), 1522-1531.

Schabath, R., Müller, G., Schubel, A., Kremmer, E., Lipp, M., & Förster, R. (1999). The murine chemokine receptor CXCR4 is tightly regulated during T cell development and activation. Journal of leukocyte biology66(6), 996-1004.

Gupta, S. K., Lysko, P. G., Pillarisetti, K., Ohlstein, E., & Stadel, J. M. (1998). Chemokine Receptors in Human Endothelial Cells FUNCTIONAL EXPRESSION OF CXCR4 AND ITS TRANSCRIPTIONAL REGULATION BY INFLAMMATORY CYTOKINES. Journal of Biological Chemistry273(7), 4282-4287.

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