Anti-Mouse CD16 / CD32 Biotin
description
The 2.4G2 antibody blocks the binding of immunoglobulins to CD16 and CD32, and possibly to Fc γ I receptor.
Additional Information
Clone:
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2.4G2
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Format:
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Biotin
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Applications:
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FC
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Reactivity:
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Mouse
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Isotype:
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Rat IgG2b
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Research Interest: | Innate Immunity |
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Cell Type: | NK and NKT Cells, Macrophage / Monocyte |
Application: | FC |
Clone: | 2.4G2 |
Preparation:
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The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
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Formulation:
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Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
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References:
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Araujo-Jorge, T. A. N. I. A., Rivera, M. T., el Bouhdidi, A. Y. A. C. H. I., Daëron, M. A. R. C., & Carlier, Y. (1993). An Fc gamma RII-, Fc gamma RIII-specific monoclonal antibody (2.4 G2) decreases acute Trypanosoma cruzi infection in mice. Infection and immunity, 61(11), 4925-4928. Jensen, W. A., Marschner, S., Ott, V. L., & Cambier, J. C. (2001). FcgammaRIIB-mediated inhibition of T-cell receptor signal transduction involves the phosphorylation of SH2-containing inositol 5-phosphatase (SHIP), dephosphorylation of the linker of activated T-cells (LAT) and inhibition of calcium mobilization. Biochemical Society Transactions, 29(Pt 6), 840-846. Vremec, D., Zorbas, M., Scollay, R., Saunders, D. J., Ardavin, C. F., Wu, L., & Shortman, K. (1992). The surface phenotype of dendritic cells purified from mouse thymus and spleen: investigation of the CD8 expression by a subpopulation of dendritic cells. The Journal of experimental medicine, 176(1), 47-58. |