Anti-Mouse CD150 (SLAM) FITC

Grouped product items
SizePrice Qty
25ug
$120.00
100ug
$310.00

Additional 9D1 Formats

Cat.No.FormatStarting From
17112-50FITC$ 120.00
Catalog Number : 17112-50

description

The 9D1 monoclonal antibody specifically binds to mouse CD150, a 75-95 kD single chain type I transmembrane glycoprotein also known as signaling lymphocyte activation molecule (SLAM). It is expressed on B cells, dendritic cells, T cells, and thymocytes. Upon activation, its expression is upregulated. SLAM signaling in Th1 cells is reported to induce IFN-γ production. The 9D1 antibody is reported to activate the CD150 receptor.

Additional Information

Clone:
9D1
Format:
FITC
Applications:
FC
Reactivity:
Mouse
Isotype:
Rat IgG1
Research Interest:Stem Cell Research
Application:FC
Clone:9D1
Preparation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Howie, D., Okamoto, S., Rietdijk, S., Clarke, K., Wang, N., Gullo, C., ... & Kuchroo, V. (2002). The role of SAP in murine CD150 (SLAM)-mediated T-cell proliferation and interferon γ production. Blood100(8), 2899-2907.

Chi, A. W., Chavez, A., Xu, L., Weber, B. N., Shestova, O., Schaffer, A., ... & Bhandoola, A. (2011). Identification of Flt3+ CD150− myeloid progenitors in adult mouse bone marrow that harbor T lymphoid developmental potential. Blood118(10), 2723-2732.

Wang, N., Satoskar, A., Faubion, W., Howie, D., Okamoto, S., Feske, S., ... & Terhorst, C. (2004). The cell surface receptor SLAM controls T cell and macrophage functions. The Journal of experimental medicine199(9), 1255-1264.

© BioGems International, Inc. All rights reserved.