Anti-Human/Mouse CD146 PE

Grouped product items
SizePrice Qty
25 tests
$110.00
100 tests
$280.00

Additional P1H12 Formats

Cat.No.FormatStarting From
18512-60PE$ 110.00
Catalog Number : 18512-60

description

The P1H12 monoclonal antibody reacts with CD146, 118kDA transmembrane glycoprotein that is also called the melanoma cell adhesion molecule (Mel-CAM), MUC18, Endo-CAM, and S-Endo. It is a prominently glycosylated protein with carbohydrates comprising the majority of its mass and it is expressed on melanoma, stromal, endothelial, and bone marrow fibroblasts. The P1H12 antibody cross reacts with human, mouse, canine, rabbit to the exclusion of rat protein.

Additional Information

Clone:
P1H12
Format:
PE
Applications:
FC
Reactivity:
Human, Mouse
Isotype:
Mouse IgG1, kappa
Cell Type:T Cells, Stem Cells
Application:FC
Clone:P1H12
Preparation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Elshal, M. F., Khan, S. S., Takahashi, Y., Solomon, M. A., & McCoy, J. P. (2005). CD146 (Mel-CAM), an adhesion marker of endothelial cells, is a novel marker of lymphocyte subset activation in normal peripheral blood. Blood,106(8), 2923-2924.

Shih, I. M. (1999). The role of CD146 (Mel‐CAM) in biology and pathology. The Journal of pathology189(1), 4-11.

Solovey, A. N., Gui, L., Chang, L., Enenstein, J., Browne, P. V., & Hebbel, R. P. (2001). Identification and functional assessment of endothelial P1H12.Journal of Laboratory and Clinical Medicine138(5), 322-331.

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