Anti-Mouse CD117 (c-Kit) PE-Cyanine7
Additional ACK2 Formats
Cat.No. | Format | Starting From |
---|---|---|
19112-60 | PE | $ 50.00 |
19112-20 | Purified | $ 115.00 |
19112-25 | SAFIRE Purified | $ 135.00 |
19112-80 | APC | $ 70.00 |
19112-77 | PE-Cyanine7 | $ 65.00 |
description
The ACK2 monoclonal antibody specifically reacts with mouse CD117 (c-Kit receptor), a 145 kDa transmembrane tyrosine-kinase receptor encoded by the Kit gene. The c-Kit receptor, also known as stem cell factor receptor, is expressed on hematopoietic progenitor cells in adult bone marrow, in progenitors of erythroid and myeloid lineages, and precursors of B and T cells. CD117 enhances the proliferation and the differentiation of the hematopoietic progenitor cells and seems to enhance the development of T cells, as the c-Kit receptor and its ligand are expressed by the thymus.
Additional Information
Clone:
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ACK2
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Format:
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PE-Cyanine7
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Applications:
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FC
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Reactivity:
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Mouse
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Isotype:
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Rat IgG2b, kappa
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Research Interest: | Angiogenesis |
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Cell Type: | Stem Cells |
Application: | FC |
Clone: | ACK2 |
Preparation:
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The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
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Formulation:
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Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
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References:
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Godfrey, D. I., Kennedy, J., Mombaerts, P., Tonegawa, S., & Zlotnik, A. (1994). Onset of TCR-beta gene rearrangement and role of TCR-beta expression during CD3-CD4-CD8-thymocyte differentiation. The Journal of Immunology, 152(10), 4783-4792. Godfrey, D. I., Zlotnik, A. L. B. E. R. T., & Suda, T. A. K. A. S. H. I. (1992). Phenotypic and functional characterization of c-kit expression during intrathymic T cell development. The Journal of Immunology, 149(7), 2281-2285. Feng, H., Sandlow, J. I., & Sandra, A. (1998). The c-kit receptor and its possible signaling transduction pathway in mouse spermatozoa. Molecular reproduction and development, 49(3), 317-326. |