Anti-Mouse CD103 (Integrin alpha E) APC
Additional 2E7 Formats
| Cat.No. | Format | Starting From |
|---|---|---|
| 15112-25 | SAFIRE Purified | $ 355.00 |
| 15112-80 | APC | $ 195.00 |
Catalog Number : 15112-80
description
The 2E7 monoclonal antibody specifically reacts with mouse CD103, a type I transmembrane glycoprotein in the integrin family that bind to E-cadherin. CD103 is expressed on intraepithelial lymphocyte T cells, peripheral regulatory T cells, lamina propria T cells, and a subset of dendritic cells. It is reported to be involved in T cell homing and immune system regulation.
Additional Information
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Clone:
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2E7
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Format:
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APC
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Applications:
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FC
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Reactivity:
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Mouse
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Isotype:
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Armenian Hamster IgG
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| Research Interest: | Adaptive Immunity |
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| Cell Type: | T Cells, Dendritic Cells, T Regulatory Cells |
| Application: | FC |
| Clone: | 2E7 |
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Preparation:
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The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
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Formulation:
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Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
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References:
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Hadley, G. A., Bartlett, S. T., Via, C. S., Rostapshova, E. A., & Moainie, S. (1997). The epithelial cell-specific integrin, CD103 (alpha E integrin), defines a novel subset of alloreactive CD8+ CTL. The Journal of Immunology, 159(8), 3748-3756. Schön, M. P., Schön, M., Parker, C. M., & Williams, I. R. (2002). Dendritic Epidermal T Cells (DETC) are Diminished in Integrin &agr; E (CD103)-Deficient Mice. Journal of investigative dermatology, 119(1), 190-193. Zikri, N. N., Schumer, E., Wang, J. J., Gaughan, A., Hadley, G. A., & Moffatt-Bruce, S. D. (2010). Induction of CD4< sup>+</sup> CD25< sup>+</sup> T Regulatory Cells with CD103 Depletion. Journal of Surgical Research, 163(1), 162-168. |