Anti-Human GARP FITC
Catalog Number : 77111-50
description
The GARP5 monoclonal antibody specifically reacts with human Glycoprotein A Repetitions Predominant (GARP, also known as LRRC32 or Garpin) molecule, a 80 kDa transmembrane glycoprotein expressed on the cell surface. GARP is expressed in activated Treg cells, placenta, pancreas, liver, skeletal muscle, heart, lung, and kidney, and it acts as a receptor for latent TGF-β, which down-regulates the Treg cells action.
Additional Information
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Clone:
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GARP5
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Format:
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FITC
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Applications:
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FC
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Reactivity:
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Human
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Isotype:
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Mouse IgG1
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| Research Interest: | Adaptive Immunity |
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| Cell Type: | T Cells, T Regulatory Cells |
| Application: | FC |
| Clone: | GARP5 |
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Preparation:
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The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
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Formulation:
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Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
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References:
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Wang, R., Zhu, J., Dong, X., Shi, M., Lu, C., & Springer, T. A. (2012). GARP regulates the bioavailability and activation of TGFβ. Molecular biology of the cell,23(6), 1129-1139. |