Anti-Human CD8a PE

Grouped product items
SizePrice Qty
25 tests
$50.00
100 tests
$110.00
500 tests
$470.00

Additional RPA-T8 Formats

Cat.No.FormatStarting From
10131-20Purified$ 90.00
10131-77PE-Cyanine7$ 85.00
10131-40BG Violet 450$ 85.00
10131-50FITC$ 45.00
10131-87APC-Cyanine7 $ 115.00
10131-80APC$ 70.00
10131-60PE$ 50.00
10131-70PerCP-Cyanine5.5 $ 90.00
10131-30Biotin$ 65.00
10131-45BG Violet 500$ 110.00
Catalog Number : 10131-60

description

The RPA-T8 monoclonal antibody specifically reacts with the human CD8a molecule, a 32 kDa cell surface receptor expressed either as a heterodimer (CD8 α/β) or as a homodimer (CD8 α/α) on the majority of thymocytes, a subpopulation of mature T cells, and natural killer cells. CD8 interacts with the major histocompatibility complex class I (MHC class I) molecules on antigen-presenting cells or epithelial cells. The RPA-T8 antibody reacts with 13-48% of peripheral lymphocytes, 80% of thymocytes, and a subset of natural killer cells.

RPA-T8, OKT8, and HIT8a antibodies do not compete with each other for binding to peripheral leukocytes, meaning that that they do not recognize the same epitope or block each other by steric hindrance.

product image
Human peripheral blood lymphocytes were stained with PE RPA-T8 with relevant isotype control in Gray
product image

Additional Information

Clone:
RPA-T8
Format:
PE
Applications:
FC
Reactivity:
Human
Isotype:
Mouse IgG1, kappa
Research Interest:Adaptive Immunity
Cell Type:NK and NKT Cells, T Cells
Application:FC
Clone:RPA-T8
Preparation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Knapp W (1989) Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.

Schlossman, S., L. Bloumsell, et al. eds (1995). Leucocyte Typing V: White Cell Differentiation Antigens. Oxford University Press. New York

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