Anti-Human CD8a APC

Grouped product items
Size Price Qty
25 tests
$105.00
100 tests
$220.00

Additional Hit8a Formats

Cat.No. Format Starting From
10111-20 Purified $ 95.00
10111-50 FITC $ 40.00
10111-60 PE $ 50.00
10111-40 BG Violet 450 $ 105.00
10111-80 APC $ 105.00
Catalog Number : 10111-80

description

The Hit8a monoclonal antibody reacts with the human CD8a molecule, a 32 kDa cell surface receptor expressed either as a heterodimer (CD8 α/β) or as a homodimer (CD8 α/α) on the majority of thymocytes, a subpopulation of mature T cells, and natural killer cells. CD8 interacts with the major histocompatibility complex class I (MHC class I) molecules on antigen-presenting cells or epithelial cells. The Hit8a antibody reacts with 13-48% of peripheral lymphocytes, 80% of thymocytes, and a subset of natural killer cells.

HIT8a, RPA-T8, and OKT8 antibodies do not compete with each other for binding to peripheral leukocytes, meaning that that they do not recognize the same epitope or block each other by steric hindrance.

Additional Information

Clone:
Hit8a
Format:
APC
Applications:
FC
Reactivity:
Human
Isotype:
Mouse IgG1, kappa
Research Interest: Adaptive Immunity
Cell Type: NK and NKT Cells
Application: FC
Clone: Hit8a
Preparation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Schlossman, S., L. Bloumsell, et al. eds (1995). Leucocyte Typing V: White Cell Differentiation Antigens. Oxford University Press. New York

Barclay, A. N., Brown, M. H., Law, S. A. K. A., McKnight, A. J., Tomlinson, M. G., & van der Merwe, P. A. (1997). The leucocyte antigen factsbook. Academic Press.

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