Anti-Human CD42b PE

Grouped product items
SizePrice Qty
100 tests
$240.00

Additional HIP1 Formats

Cat.No.FormatStarting From
04511-50FITC$ 100.00
04511-60PE$ 240.00
04511-20Purified$ 55.00
Catalog Number : 04511-60

description

The HIP1 monoclonal antibody specifically binds to human CD42b, a 145kDa transmembrane protein known as the platelet glycoprotein Ib alpha chain (gpIbα). CD42 is expressed on platelets and megakaryocytes and is reported to be involved in platelet adhesion. The HIP1 antibody inhibits collage-induced aggregation and platelet to von Willebrand Factor (vWF) binding.

Additional Information

Clone:
HIP1
Format:
PE
Applications:
FC
Reactivity:
Human
Isotype:
Mouse IgG1, kappa
Application:FC
Clone:HIP1
Preparation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Gohda, F., Uchiumi, H., Handa, H., Matsushima, T., Tsukamoto, N., Morita, K., ... & Karasawa, M. (2007). Identification of inherited macrothrombocytopenias based on mean platelet volume among patients diagnosed with idiopathic thrombocytopenia. Thrombosis research119(6), 741-746.

George, N. P. E., Wei, Q., Shin, P. K., Konstantopoulos, K., & Ross, J. M. (2006). Staphylococcus aureus adhesion via Spa, ClfA, and SdrCDE to immobilized platelets demonstrates shear-dependent behavior. Arteriosclerosis, thrombosis, and vascular biology26(10), 2394-2400.

Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.

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