Anti-Human CD33 FITC
Catalog Number : 05411-50
description
The WM53 monoclonal antibody specifically reacts with human CD33, a 67 kDA transmembrane glycoprotein also known as GP67 and P67. CD33 is expressed on monocytes, granulocytes, dendritic cells, mast cells, and myeloid progenitors to the exclusion of hematopoietic stem cells, lymphocytes, and platelets. It functions to assist sialic acid-dependent cell adhesion.
Additional Information
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Clone:
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WM53
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Format:
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FITC
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Applications:
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FC
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Reactivity:
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Human
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Isotype:
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Mouse IgG1, kappa
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| Cell Type: | Macrophage / Monocyte |
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| Application: | FC |
| Clone: | WM53 |
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Preparation:
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The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
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Formulation:
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Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
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References:
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Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989. Favaloro, E. J., Bradstock, K. F., Kabral, A., Grimsley, P., Zowtyj, H., & Zola, H. (1988). Further characterization of human myeloid antigens (gp160, 95; gp150; gp67): investigation of epitopic heterogeneity and non‐haemopoietic distribution using panels of monoclonal antibodies belonging to CD‐11b, CD‐13 and CD‐33. British journal of haematology, 69(2), 163-171. Freeman, S. D., Kelm, S., Barber, E. K., & Crocker, P. R. (1995). Characterization of CD33 as a new member of the sialoadhesin family of cellular interaction molecules. Blood, 85(8), 2005-2012. |