Anti-Human CD3 APC

Grouped product items
SizePrice Qty
25 tests
$65.00
100 tests
$130.00

Additional OKT3 Formats

Cat.No.FormatStarting From
05121-20Purified$ 115.00
05121-25SAFIRE Purified$ 160.00
05121-40BG Violet 450$ 95.00
05121-60PE$ 50.00
05121-80APC$ 65.00
05121-50FITC$ 40.00
05121-70PerCP-Cyanine5.5 $ 135.00
05121-77PE-Cyanine7$ 95.00
Catalog Number : 05121-80

description

The OKT3 monoclonal antibody specifically reacts with the ε chain of the CD3/T lymphocyte antigen receptor complex. The CD3 complex contains γ, δ, and ε chains, and it is part of the TCR complex, expressed by all mature T lymphocytes and by the thymocyte lineage. CD3 enhances the antigen recognition by signal transduction.

The OKT3 antibody is an immunosuppressive, which has proven to be an effective therapeutic agent in liver, heart, and renal allograft rejection.

Additional Information

Clone:
OKT3
Format:
APC
Applications:
FC
Reactivity:
Human
Isotype:
Mouse IgG2a, kappa
Research Interest:Adaptive Immunity
Cell Type:NK and NKT Cells, T Cells, T Regulatory Cells, Th17 cells
Application:FC
Clone:OKT3
Preparation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Schlossman, S., L. Bloumsell, et al. eds (1995). Leucocyte Typing V: White Cell Differentiation Antigens. Oxford University Press. New York

Knapp W (1989) Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.

Adair, J. R., Athwal, D. S., Bodmer, M. W., Bright, S. M., Collins, A. M., Pulito, V. L., ... & Jolliffe, L. K. (1994). Humanization of the murine anti-human CD3 monoclonal antibody OKT3. Human Antibodies5(1), 41-47.

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