Anti-Human CD289 (TLR9) PE
Rat IgG2a, kappa
|Research Interest:||Innate Immunity|
|Cell Type:||Macrophage / Monocyte, Dendritic Cells|
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Latz, E., Schoenemeyer, A., Visintin, A., Fitzgerald, K. A., Monks, B. G., Knetter, C. F., ... & Golenbock, D. T. (2004). TLR9 signals after translocating from the ER to CpG DNA in the lysosome. Nature immunology, 5(2), 190-198.
Leifer, C. A., Kennedy, M. N., Mazzoni, A., Lee, C., Kruhlak, M. J., & Segal, D. M. (2004). TLR9 is localized in the endoplasmic reticulum prior to stimulation.The Journal of Immunology, 173(2), 1179-1183.
József, L., Khreiss, T., El Kebir, D., & Filep, J. G. (2006). Activation of TLR-9 induces IL-8 secretion through peroxynitrite signaling in human neutrophils. The Journal of immunology, 176(2), 1195-1202.