Anti-Human CD206 (MMR) APC
Catalog Number : 28111-80
description
The 19.2 monoclonal antibody specifically reacts with human CD206, type I transmembrane protein primarily present on the surface of macrophages, immature dendritic cells, and the surface of skin cells. The receptor recognizes a range of microbial carbohydrates and is involved in macrophage activation and antigen presentation.
Additional Information
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Clone:
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19.2
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Format:
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APC
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Applications:
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FC
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Reactivity:
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Human
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Isotype:
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Mouse IgG1, kappa
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| Research Interest: | Innate Immunity |
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| Cell Type: | Macrophage / Monocyte |
| Application: | FC |
| Clone: | 19.2 |
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Preparation:
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The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
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Formulation:
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Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
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References:
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Dasgupta, S., Bayry, J., Lacroix-Desmazes, S., & Kaveri, S. V. (2007). Human mannose receptor (CD206) in immune response: novel insights into vaccination strategies using a humanized mouse model. Expert review of clinical immunology, 3(5), 677-681. Tsai, Y. M., Hsu, S. C., Zhang, J., Zhou, Y. F., Plunkett, B., Huang, S. K., & Gao, P. S. (2013). Functional interaction of cockroach allergens and mannose receptor (CD206) in human circulating fibrocytes. PloS one, 8(5). Alves‐Januzzi, A. B., Brunialti, M. K. C., & Salomao, R. (2017). CD 163 and CD 206 expression does not correlate with tolerance and cytokine production in LPS‐tolerant human monocytes. Cytometry Part B: Clinical Cytometry, 92(3), 192-199. |